It said most of the extra deaths would happen in patients having
colorectal surgery, blood cancer chemotherapy and hip replacements.
UK experts said the study confirmed their fears that antibiotic resistance would affect routine surgery.
England's chief medical officer has called the issue a "ticking time bomb".
In this report,
a team of scientists from a number of different American institutions
estimated that as many as half of all bacteria that cause infections
after surgery are resistant to antibiotics in the US.
They also estimated that one in four infections treated with antibiotics after chemotherapy treatment was now drug-resistant.
For
the report, the researchers looked at what could happen to people
having common operations and being treated for cancer with chemotherapy
if antibiotic resistance increased by a third - in line with current
trends.
They calculated that in the US there would be 120,000 more infections and 6,300 more deaths each year.
Lead
study author Prof Ramanan Laxminarayan, director of the Centre for
Disease Dynamics, Economics and Policy in Washington DC, said
antibiotics were the bedrock of modern medicine but their reduced
effectiveness was a "significant challenge".
He explained: "The danger is that antibiotic resistance is squeezing the value out of modern medicine."
He
said antibiotic resistance was already killing newborns in the
developing world and mostly elderly people in the developed world.
And as the elderly population increased, they would have more operations and be more at risk of infections, he said.
He
urged public health experts to come up with "new strategies for the
prevention and control of antibiotic resistance at national and
international levels".
Antibiotic Resistance |
'Undermining treatment'
Prof
Laura Piddock, director of Antibiotic Action and professor of
microbiology at the University of Birmingham, has previously warned of
the potential effects of antibiotic resistance on routine operations.
"It
is good to see evidence from the US that supports these serious
concerns that antibiotic resistance will impact upon many areas of
medicine, including that it is undermining the treatment of cancer
patients."
She said she hoped the report would be "a loud 'wake-up
call' to pharmaceutical companies" to research and develop new
treatment for bacterial infections.
"Without them, patients will
be less likely to survive cancer and so unable to take advantage of new
life-extending cancer therapies," she said.
However, in the UK at present, there are no major signs of antibiotics failing to control infections after routine surgery.
In fact, data shows that UK infection rates are falling slightly, according to a Public Health England report.
But Prof Nigel Brown, President of the Microbiology Society, said the study was relevant to the UK.
"Antibiotic
resistance is a global problem and it is likely that routine surgery
such as hip replacement and elective caesarean sections will become much
rarer in the UK, unless steps are taken to prevent its spread."
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